Bio Chemistry Question:

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How is the cooling of organs and tissues for medical transplantations associated with the effect of temperature upon enzymatic reactions?

Bio Chemistry Interview Question
Bio Chemistry Interview Question

Answer:

The molecular degradation during the decomposition of organs and tissues is catalyzed by enzymes. The cooling to adequate temperatures of some organs and tissues destined to transplantation reduces that enzyme activity and thus lessens the natural decomposition process. By the same rational the cooling reduces the metabolic work of cells and prevents that, they degrade their own structures to obtain energy. Elevation of temperature later revert denaturation of enzymes and the organs and tissues also preserved by other specific techniques may be grafted into the receptors.

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Concerning enzymatic reactions how different, are the graphic curve of the variation of the speed of a reaction as function of substrate concentration and the curve of variation of the speed of a reaction as function of temperature?Does pH affect the enzyme activity?