Bio Chemistry Question:
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How is the cooling of organs and tissues for medical transplantations associated with the effect of temperature upon enzymatic reactions?
Answer:
The molecular degradation during the decomposition of organs and tissues is catalyzed by enzymes. The cooling to adequate temperatures of some organs and tissues destined to transplantation reduces that enzyme activity and thus lessens the natural decomposition process. By the same rational the cooling reduces the metabolic work of cells and prevents that, they degrade their own structures to obtain energy. Elevation of temperature later revert denaturation of enzymes and the organs and tissues also preserved by other specific techniques may be grafted into the receptors.
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