Immunology Interview Questions & Answers Download PDF
Immunology Interview Questions and Answers will guide us now that Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. Immunology deals with, among other things, the physiological functioning of the immune system in states of both health and disease. Learn conceptual Immunology or get preparation of Immunology jobs interview by our this Immunology Interview Questions and Answers Guide.
200 Immunology Questions and Answers:
Immunology Interview Questions Table of Contents:
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1 :: Expand cell line HL-60.
Human myeloid leukemia cell line
2 :: How B cell hybridomass are formed?
They are formed by the fusion of antigen primed B cells with cancerous plasma cells.
3 :: Name the assay method for insulin in serum.
ELISA or RIA
5 :: Name the assay method for compliment component C3 on glomerullar basement membrane.
Immunofluorescence
6 :: Name the assay method for IgG in serum.
The method is ELISA.
7 :: What does the following sentence means? T cell is said to be class I restricted.
It means that they can recognize the antigen, which is, associated with class I MHC molecules.
8 :: Describe major events in the inflammatory response.
The following are the major events in the inflammatory response:
The diameter of the capillaries increases in the affected region and their permeability, which facilitates influx of white blood cells.
The diameter of the capillaries increases in the affected region and their permeability, which facilitates influx of white blood cells.
9 :: Name some features of a secondary immune response that distinguish it from primary immune response
Secondary immune response requires an amplified population of memory cells. Response is more rapid compared to primary immune response.
10 :: Give an example for alloantigen
Blood group antigens are alloantigens.
11 :: What is the other name of isoantigen?
The other name is Alloantigen.
12 :: What is an iso antigen?
It is produced only by some members of a species but not the others. These are capable of eliciting immune response in the individuals that lack the antigen.
13 :: What is i-gene?
It is a bacterial gene, that code for lac operon- repressor protein.
14 :: What is immunoblotting?
This is a technique to determine the presence of an antigen by the reaction of labeled antibodies to the antigen. This is done after separating the antigens according to the size or charge by gel electrophoresis.
15 :: What is immunolabeling?
Labeling molecules by the use of antibodies bound to another molecule that serves as labels for an antigen antibody complex.
16 :: What is an intron?
The nucleotide sequence present between exons of a gene. They can be removed by the process of splicing.
17 :: What is an exon?
Exon is a region of a gene that contains coding sequences for a “polypeptide”.
18 :: What is the host defense mechanism shown if the infection is through toxin-induced damage of host cells?
Neutralization of toxin by antibodies
19 :: What is the host defense mechanism shown if the infection is through invasion of host tissues?
Antibody mediated agglutination.
20 :: What is the host defense mechanism shown if the infection is through proliferation?
Phagocytosis compliment mediated lysis localized inflammatory response.
21 :: What is the host defense mechanism shown if an attachment is made to host cell?
Blockage of attachment by secretory IgA antibodies
22 :: What is the response type and activity shown by effector molecule natural killer cell macrophages?
Cell mediated immune response.
Activity: Kills virus infected cells by ADCC.
Activity: Kills virus infected cells by ADCC.
23 :: What is the response type and activity shown by effectors molecule cytotoxic T cells?
Cell mediated immune response.
Activity: Kills virus infected self-cells.
Activity: Kills virus infected self-cells.
24 :: What is the response type and activity shown by effectors molecule IFN ? secreted by TH or TC cell?
Cell mediated immune response.
25 :: What is the response type and activity shown by effectors molecule compliment activated by IgG or IgM?
Mediated opsonization
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