Physiology Question:
Download Questions PDF

Please tell me about some drugs that can cross the blood brain barrier?

Physiology Interview Question
Physiology Interview Question

Answer:

Any drug that is designed to be given orally, i.m. s.c. or i.v. and acts on the brain MUST cross the blood-brain barrier.

E.g. Opiates, anxiolytics, SSRI's, anti-psychotics

Drug needs to be lipid (fat) soluble to cross the BBB.

Download Physiology Interview Questions And Answers PDF

Previous QuestionNext Question
Explain How is the calculation derived for a drug to be bioequivalent with other? On which base the limit is fixed as 80-120% for a drug to be bioequivalent. What is meant by 90% confidential interval?Explain How is the concentration of drugs in human plasma defined?