Pharmacology Interview Preparation Guide

Enhance your Pharmacology interview preparation with our set of 21 carefully chosen questions. These questions will test your expertise and readiness for any Pharmacology interview scenario. Ideal for candidates of all levels, this collection is a must-have for your study plan. Secure the free PDF to access all 21 questions and guarantee your preparation for your Pharmacology interview. This guide is crucial for enhancing your readiness and self-assurance.
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21 Pharmacology Questions and Answers:

1 :: Explain Do you know how the dose for children is being estimated based on preclinical data?

There are a number of ways of estimating children's doses from preclinical (adult) data - often depends on the therapeutic index of the drug in question (the wider the therapeutic window the less accurate the child's dose needs to be). Sometimes straight weight-basis i.e. 7kg child gets 1/10 dose of 70kg adult.

More accurate (so they say) is a dose based on body surface area (child's surface area is greater in proportion to its body weight than an adult is). There are normograms to calculate surface area from weight and height of child.

All of these may be wrong if clearance of drug in child is significantly different from adult e.g. different metabolism or different route of clearance.
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2 :: Explain All of the following agents are beta receptor agonists EXCEPT:
Epinephrine
Isoproterenol
Methoxamine
Dobutamine?

Methoxamine

3 :: Explain Which of the following barbiturates is an ultra-short-acting drug?

Secobarbital
Amobarbital
Thiopental
Phenobarbital?

Thiopental

4 :: Explain DOC for cisplatin induced vomitting:

metaclopramide
domperidone
ondansetron
prochlorperazine?

ondansetron

5 :: Explain Ciprofloxacin act by

Inhibiting protein synthesis
Inhibiting DNA function
Inhibiting cell wall synthesis
Inhibiting glycolysis?

Inhibiting DNA function
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6 :: Indicate the irreversible alfa receptor antagonist:

Tolazoline
Labetalol
Prazosin
Phenoxybenzamine

Phenoxybenzamine

7 :: MOA of moricizine:

prolongs APD
shortens APD
no change in APD
calcium channel blecker

prolongs APD

8 :: Explain which of the following antitubercular drug contraindicated in pragnancy.

INH
ethambutol
rifampicin
streptomycin

streptomycin

9 :: Explain Hypnotic drugs are used to treat:

Psychosis
Sleep disorders
Narcolepsy
Parkinsonian disorders

Sleep disorders

10 :: Indicate a beta receptor antagonist, which has very long duration of action:

Metoprolol
Propranolol
Nadolol
Pindolol

Nadolol
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