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What is deference between the working standard and reference standard?
Answers:
Answer #1Reference std is like USP,EP std , in this std we get COA
including results of Potency by HPLC , NMR & XRPD data.
whenever there is requirement of w.std preparation first we
have get API rawmaterial from warehouse & we check assay ,
water content or LOD & Related substances aganist reference
std . Some times we are doing analysis in duplicate & get
mean value.then we decide final assay or potency value &
it's validity one year
including results of Potency by HPLC , NMR & XRPD data.
whenever there is requirement of w.std preparation first we
have get API rawmaterial from warehouse & we check assay ,
water content or LOD & Related substances aganist reference
std . Some times we are doing analysis in duplicate & get
mean value.then we decide final assay or potency value &
it's validity one year
Answer #2Working standard is internally use and refrence is external
Answer #3Reference standard is the one completely characterized material.
Working standard is the one qualified against reference standard with minimal testing's.
Working standard is the one qualified against reference standard with minimal testing's.
Answer #4Working standard is internal preparationand reference standard like usp, ip
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