Front End Developer (AngularJS) Question:

The startup time heavily depends on your network connection, state of the cache, browser used and available hardware, but typically we measure bootstrap time in tens or hundreds of milliseconds.

The runtime performance will vary depending on the number and complexity of bindings on the page as well as the speed of your backend (for apps that fetch data from the backend). Just for an illustration we typically build snappy apps with hundreds or thousands of active bindings.