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Treatment of oligodendrogliomas may include the following:

Surgery, usually with radiation therapy.
A clinical trial of surgery and radiation therapy with or without chemotherapy for tumors that cannot be completely removed by surgery.
A clinical trial of chemotherapy using one or more drugs.

Treatment of anaplastic oligodendroglioma may include the following:

Surgery plus radiation therapy with or without chemotherapy.
Chemotherapy using more than one drug.
Radiation therapy with or without chemotherapy using more than one drug.
Clinical trials of new treatments.